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产品目录

重组大鼠IL-22图片
产品货号:
GS4861
中文名称:
重组大鼠IL-22
英文名称:
Recombinant Rat Interleukin 22
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately16.6kDa,a single non-glycosylated polypeptide chain containing 146 amino acids.
储存条件:冷冻(-20℃)

概述

IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.Recombinant rat Interleukin-22 contains 146 amino acids and it has approximately 79%and 92%amino acid sequence identity with human and murine IL-22.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>97%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg.
成分Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素Less than 1 EU/μg of rRtIL-22 as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列LPINSQCKLE AANFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEELFRGV KAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSIHLSPCH ISGDDQNIQK NVRQLKETVQ KLGESGEIKA IGELDLLFMS LRNACV

相关搜索:重组大鼠IL-22IL-22, RatRecombinant Rat Interleukin 22
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